| SPC | Solid Phase Crystallization | - | Computer Acronyms(common) |
| SPC | Statistical Process Control | - | Computer Acronyms(common) |
| SPC | Shipping And Packing Cost | - | Organizations |
| SPC | Shuttle Processing Contractor | - | Organizations |
| SPC | Starting Point Code | - | Organizations |
| SPC | Stored Program Command | - | Organizations |
| SPC | Synoptic Properties Code | - | Organizations |
| SPC | Secretariat Of The Pacific Community | - | Astronomy |
| SPC | Small Particle Count (or Counter) | - | Business and Finance |
| SPC | Sector Processing Center | - | Business and Finance |
| SPC | Storm Prediction Center | - | Business and Finance |
| SPC | soft permanent connection
| - | Human Genome |
