| ACL | Alternative Concentration Limit | - | Computer Acronyms(common) |
| ACL | Analytical Chemistry Laboratory | - | Computer Acronyms(common) |
| ACL | Average Contaminant Level | - | Computer Acronyms(common) |
| ACL | Access Control List | - | Computer and Internet |
| ACL | Access Control List | - | Human Genome |
| ACL | Anterior Cruciate Ligament | - | Medical(slang) |
| ACL | Access Control List - Anterior Cruciate Ligament | - | Astronomy |
| ACL | Advanced Computing Laboratory | - | Business and Finance |
| ACL | Alternative Concentration Level/limit | - | Business and Finance |
| ACL | Auxiliary Cooling Loop | - | Business and Finance |
